氫水還原健康–氫氣治療新生兒腦缺血的實驗

 

日本學者07Nature Med Ohsawa et al. 2007 )文章發表後,立刻引起我們的極大興趣。我們採用不同的腦缺血模型,驗證呼吸 2% 氫氣是否可治療腦缺血損傷,研究結果與日本學者的結果類似,證明呼吸 2% 氫氣確實能夠治療新生兒缺血缺氧後損傷。該內容已發表文章,見 Cai JM, Kang ZM, Liu W, et al. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci lett 2008,441(2):167-172. 文章發表後,立刻引起關注,目前已經被引用 6次。這個文章是我們的第一篇關於氫的文章, 比日本學者第一篇晚了1. 但是我們的速度也是比較快的

 

Abstract: Hypoxia-ischemia (HI) brain injury is a major cause of neuronal cell death especially apoptosis in the perinatal period. This study was designated to examine the effect of hydrogen therapy on apoptosis in an established neonatal HI rat pup model. Seven-day -old rat pups were subjected to left common carotid artery ligation and then 90 min hypoxia (8% oxygen at 37 °C). Immediately after HI insult, pups were placed into a chamber filled with 2% H2 for 30 min, 60 min, or 120 min, respectively. 24 hr after 2% H2 therapy, the pups were decapitated and brain injury was assessed by 2,3,5-triphenyltetrazoliumchloride (TTC), Nissl, and TUNEL staining, as well as caspase-3, caspase- 12 activities in the cortex and hippocampus. H2 treatment in a duration dependent manner significantly reduced the number of positive TUNEL cells and suppressed caspase-3 and -12 activities. These results indicated H2 administration after HI appeared to provide brain protection via inhibition of neuronal apoptosis . 

被引用文獻目錄

Ohsawa I, Nishimaki K, Yamagata K, et al. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.Biochem Biophys Res Commun, 2008, 377(4):1195-8

Ohta S.Hydrogen gas and hydrogen water act as a therapeutic and preventive antioxidant with a novel concept Nippon Ronen Igakkai Zasshi. 2008,45(4):355-62.

Taniguchi H, Andreasson K.The hypoxic-ischemic encephalopathy model of perinatal ischemia.J Vis Exp. 2008 Nov 19;(21) pii: 955. doi: 10.3791/955

Cai JM, Kang ZM, Liu K, et al. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Res. 2008 Nov 27. [Epub ahead of print]

Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S.Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.Cancer Chemother Pharmacol. 2009 Jan 16. [Epub ahead of print]

Gerald A. Matchett, Nancy Fathali, Yu Hasegawa, et al. Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models, Brain Res. 2009, doi:10.1016/j.brainres.2008.12.066

全文

 

 


 

  

TEL:0963-210-763

email: ddh2water@gmail.com

台灣氫水實驗室部落格:http://blog.xuite.net/hworker77086600/twblog

歡迎來電索取氫水辨認方法(防止喝到傷身的假氫水) 

氫水,氫分子、氫氣、健康氫水,水素水,負電位,ORP,抗氧化,抗自由基,氫分子醫學,氫水,Hydrogen water,氫氣、氫,台灣氫水研究中心,氫思語,孫學軍,太田成男,鹼性離子水,小分子水,能量水,電解水,富氫水,負氫水,活水,健康,養生,活力,大氫鬆,小氫鬆,氫水機,水素,水素水機,王群光,氫氧機,綠加利,活美水素水,低氘水,活性原子氫,富氫水,負氫水,每日水素,活氫水,氫氧造水機,百樂,負氫,氫博士,氫水棒,氫源,新德美,HOH,鹼性活氫水,氫美機,負氫離子水,氫氣棒,呼吸氫氣,氫氧療法,加氫水,氫水、健康氫水、水素水、負電位、ORP、抗氧化、抗自由基 、氫分子醫學、氫水、Hydrogen water、氫氣、氫、氫水、台灣氫水實驗室、台灣氫水研究中心、氫思語、孫學軍、太田成男、鹼性離子水、小分子水、能量水、電解水、富氫水、負氫水、活水、健康、養生、活力、大氫鬆、小氫鬆、氫水機、水素、水素水機、王群光、氫氧機、綠加利、活美水素水、低氘水、活性原子氫、富氫水、負氫水、每日水素、活氫水、氫氧造水機、百樂、負氫、氫博士、氫水棒、氫源、新德美、HOH、鹼性活氫水、氫美機、負氫離子

提供玻璃瓶裝飽和氫水供對比,免費兩瓶給你測試,收運費120元。(運費是宅配業者收去的)

 

氫水、健康氫水、水素水、負電位、ORP、抗氧化、抗自由基 、氫分子醫學、氫水、Hydrogen water、氫氣、氫、氫水、台灣氫水實驗室、台灣氫水研究中心、氫思語、孫學軍、太田成男、鹼性離子水、小分子水、能量水、電解水、富氫水、負氫水、活水、健康、養生、活力、大氫鬆、小氫鬆、氫水機、水素、水素水機、王群光氫氧機綠加利活美水素水低氘水活性原子氫富氫水負氫水每日水素活氫水氫氧造水機百樂負氫氫博士氫水棒氫源新德美HOH鹼性活氫水、氫美機、負氫離子

 

 

 

Copyright © 2017 台灣低氘"氫水"實驗室|維護: wpweaver